7-Hydroxymitragynine Legality: State-by-State Guide 2026

The chemical, known as 7- hydroxymitragynine, is a component of kratom, a plant native to Southeast Asia that has gained popularity in the U.S. as an unapproved treatment for pain, anxiety and drug dependence. Current law regulates the sale of natural kratom while maintaining the ban on synthetic alkaloids. According to recent news, Florida’s AG Attorney General banned concentrated 7-OH products, although kratom remains mostly legal.

Every kratom bill in every U.S. state, refreshed daily before markets open.

Natural kratom leaf is naturally dominant in mitragynine, with 7-OH present only in trace amounts. The flagged products included tablets, gummies, drink mixes, and shots — formats the agency says are sometimes disguised or marketed as ordinary kratom even though they deliver a far more potent, concentrated compound. Food and Drug Administration, which issued warning letters to seven companies for illegally distributing products containing concentrated 7-hydroxymitragynine (7-OH). The Board of Pharmacy is considering extending the ban to natural kratom too. The permanent ban on synthetic kratom comes from a rule set by the Joint Committee on Agency Rule Review, known as JCARR, following a hearing in April.

US health officials crack down on kratom-related products

According to Health and Human Services Secretary Robert F. Kennedy Jr., who’s launching a federal crackdown on 7-OH — the synthetic byproduct of the kratom plant — it’s dangerous. Current federal and state actions specifically target concentrated 7-OH products, not natural kratom leaf. For example, Tennessee has explicitly banned synthetic alkaloids while permitting natural plant products. Despite their wide availability, kratom-derived and 7-OH products are not legally approved for sale for consumption online or in stores and are often misleadingly labeled and promoted as “safer" alternatives to opioids for the relief of pain and other issues. Most states regulate whole-leaf kratom through Kratom Consumer Protection Acts that set a 21+ age minimum, require accurate labeling, and prohibit adulterated or synthetic products. But many medical experts and state lawmakers say all forms of kratom are dangerous and can even be deadly, though people who use it claim it helps them manage pain without opioids or other drugs.

• Natural Life Kratom Extract Tablets
• The products offered for sale on this site are not intended to diagnose, treat, cure, mitigate or prevent any disease and/or affect any structure or function of the human body.
• In the absence of regulation, last week the Orange County Board of Supervisors passed an ordinance prohibiting the sale, distribution or possession of synthetic kratom products in any form in the county.
• But, without any scientific studies, McCurdy said kratom “should be used with a high degree of caution by athletes who have trained to be champions, not guinea pigs.”
• Now, a company that claims to sell an all-natural form of kratom is getting a lot of scrutiny on social media.
• “Not only that, it’s going to last you six to eight hours just depending on your body type and your genetic makeup,” she added.

In November 2025, the Los Angeles County Public Health Department urged retailers to immediately stop selling the products, claiming that six recent overdose deaths in Los Angeles County were tied to 7-OH ingestion. They are often labeled as a dietary supplement to help with chronic pain, anxiety, depression, and opioid withdrawal. SAN FRANCISCO (KGO) — The California Department of Public Health is sounding the alarm on Kratom, as well as a potent derivative of the plant called 7-OH. “We want to save as many people from this evil substance,” said Democratic state Assemblyman Phil Steck.

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Real Botanicals offers 7-OH Tablets for sale in 10mg and 20mg options, plus 7-OH Shots at 30mg. Any 7-OH product claiming to treat, cure, or prevent disease is making illegal claims regardless of what's inside. Synthetic and semi-synthetic 7-OH faces the strictest scrutiny. We extract from kratom, not a chemistry set.

DeWine said Ohio has already seen fatal overdoses linked to the substance. The order directs the Ohio State Pharmacy Board to hold hearings within six months on whether to classify 7-OH as a controlled substance — a move that would make it illegal to manufacture, sell, possess, or use in the state. You shouldn’t drive or operate machinery after taking kratom. Start with a small dose so you can monitor its effects. If you decide to take kratom, proceed with caution.

Kupihea's husband had a history of addiction to opioids and methamphetamines. "One of which is 7-hydroxymitragynine. And that one has some concerning opioid effects." THINC Pure products are only Kratom Events for use in states where the sale and consumption of such products are legal. Club7OH.com, PaylessKratom.com, and 36 Circles LLC assume no responsibility or liability for the use or misuse of this and all products listed on Club7OH.com.

That’s partly because kratom’s relative newness makes it undetectable in standard drug testing. “It’s caused overdose, death, sickness, hospital visits from people thinking that this is marketed as an energy drink or something to help you with aches and pains,” said FitzGerald. Derived from the kratom tree, the drug has a long history in places like Cambodia, Thailand and Malaysia. Boston could soon join a growing list of Massachusetts communities that have moved to regulate kratom, a psychoactive substance native to Southeast Asia that has gained popularity in the U.S. Stay up-to-date on the biggest health and wellness news with our weekly recap. "They’re marketed for children," RFK commented on the products at vape shops.

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The FDA is particularly concerned with the growing market of 7-OH products that may be especially appealing to children and teenagers, such as fruit-flavored gummies and ice cream cones that aren’t clearly labeled as having 7-OH content. The ingredient is being used in products that are becoming increasingly available to purchase online and at smoke shops, the agency warned. General physical side effects of kratom can include nausea, constipation, dizziness and dry mouth. According to the FDA, there were 11 deaths from 2011 to 2017 connected to kratom exposure, but almost all of them involved other drugs or contaminants. An herbal supplement that’s marketed as a cure-all for chronic pain and sold in gas stations and smoke shops is getting banned in communities across Southern California and the nation.

Take your health to the next level with functional mushroom gummies. Created in 1981, the Rockefeller Institute of Government is a public policy think tank that conducts cutting-edge, nonpartisan research and policy analysis. The Rockefeller Institute will continue to monitor the kratom policy landscape as it evolves. Some variations of these kratom consumer protection acts have been introduced this session in states like Hawaii, Idaho, Illinois, Massachusetts, Maryland, Michigan, Ohio, Pennsylvania, Washington, and Wyoming. Though several kratom bills were considered this session by the Florida legislature, their session ended in March without any of the pending bills being passed that would have maintained the status of 7-OH. Florida implemented their scheduling of 7-OH concentrated at a level of 1 percent by an August 2025 emergency order by the attorney general, not legislative action, and that ban is set to expire June 30, 2026.